Human challenge trials: A game-changer in vaccine development? Examining...
The history of using human challenge trials in developing vaccines.
View ArticleCurrent and future strategies for vaccinating against invasive pneumococcal...
Researchers reviewed the immune mechanisms employed by existing vaccines for invasive pneumococcal disease.
View ArticleCDC recommendations for pneumococcal vaccine in adults
Updated recommendations from the CDC on the use of pneumococcal vaccines in adults in the United States.
View ArticleResearchers profile new drug combinations to fight antibiotic-resistant bacteria
Antimicrobial resistance – occurring when pathogens can survive antibiotic treatment – is one of the most rapidly emerging global public health threats today.
View ArticleStudy exposes gaps in pediatric antibiotic effectiveness in Southeast Asia,...
A study in The Lancet Regional Health exposes significant gaps in the effectiveness of WHO-recommended antibiotic regimens for serious infections in Southeast Asian and Pacific children, underscoring...
View ArticleNew study highlights the need for advanced pneumococcal vaccines in the wake...
The risk factors associated with CAP caused by serotypes in the different pneumococcal vaccines.
View ArticleOver 1 million deaths linked to antimicrobial resistance in Africa
Over 1.05 million deaths were associated with antimicrobial resistance (AMR) and 250,000 deaths were attributable to AMR in the WHO African region, posing an unprecedented health threat.
View ArticleResearchers unravel the workings of Group B Strep infections in pregnant women
Researchers from Binghamton University, State University of New York are unraveling the workings of Group B Strep (GBS) infections in pregnant women, which could someday lead to a vaccine.
View ArticleInternational research collaboration leads to breakthrough in antibiotic...
The accuracy of antibiotic resistance determination from Enterococcus faecium genomes for diagnostic purposes.
View ArticleChildren battling meningitis face lifelong disability, study finds
One in three children who suffer from bacterial meningitis live with permanent neurological disabilities due to the infection.
View ArticleStudy highlights impact of government vaccine recommendations and...
A new study co-authored by a University of Massachusetts Amherst economist reveals the value of government vaccine recommendations to drugmakers, as well as potential benefits of advertising...
View ArticleStudy links pneumonia transmission in seniors to contact with young children
New research being presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April) finds that pneumonia-causing bacteria are...
View ArticleRising antibiotic resistance prompts shift to ecological research strategies...
The need to enhance research on the interactions between bacterial pathogens and commensals within human microbiomes.
View ArticleWHO updates Bacterial Priority Pathogens List to combat antimicrobial resistance
The World Health Organization (WHO) today released its updated Bacterial Priority Pathogens List (BPPL) 2024, featuring 15 families of antibiotic-resistant bacteria grouped into critical, high and...
View ArticleAmoxicillin outperforms penicillin V in treating pediatric pneumonia, study...
A recent study confirmed amoxicillin's lower risk of treatment failure compared to penicillin V in treating pediatric pneumonia, with no difference in severe complications.
View ArticleFrequent infections and pathobionts boost children's nasal immunity, study...
Dynamic interactions with viruses and bacterial pathobionts significantly enhance nasal innate immunity in children, revealing distinct immunophenotypes driven by microbial load and type.
View ArticleMapping pathogen spread and evolution using genomic and human mobility data
A new way to map the spread and evolution of pathogens, and their responses to vaccines and antibiotics, will provide key insights to help predict and prevent future outbreaks.
View ArticleBacterial communication system aids survival against antibiotics
When confronted with an antibiotic, toxic substance, or other source of considerable stress, bacteria are able to activate a defense mechanism using cell-to-cell communication to 'warn' unaffected...
View ArticleUpper respiratory microbiome shows age, sex, and lifestyle impacts, study finds
A Dutch study analyzed the upper respiratory tract microbiome across various age groups, finding significant associations between microbial composition, age, sex, and lifestyle factors like smoking and...
View ArticlePneumococcal vaccines could drastically reduce child deaths by 2030
Utilizing pneumococcal conjugate vaccines (PCVs) could save almost 700,000 children's lives between the time of their introduction to the year 2030, according to a new modeling study. This would be...
View Article